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Filling Line
Vial Filling Line

PRODUCTS

Vial Filling Line

BRIEF INTRODUCTION

JKFFL Series Vial Filling Line is a modular aseptic production system, composed of a vertical ultrasonic vial washer, a hot air circulation depyrogenation tunnel, a filling and stoppering machine, and a capping machine. The line can operate either as a fully integrated system or as individual standalone units. The complete line covers key processes including washing, drying, depyrogenation and sterilization, filling, stoppering, and capping. It is suitable for vials with volumes of 2–100 mL and meets pharmaceutical production requirements for cleanliness, sterility, and container closure integrity.

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Product Positioning

Designed to meet GMP-grade production requirements for aseptic preparations, covering the entire process of vial washing → sterilization → filling → stopper insertion → capping.

Applicable Packaging Type & Specifications

Packaging Type: Vials
Fill Volume Range: 2 – 100 mL
Maximum Output: Up to 18,000 vials/hour
(verified under 10 mL vial, liquid product conditions)

Process Flow

Infeed → Washing (Ultrasonic + Three-Water / Three-Air Spray) → Sterilization (Dry heat at 320 °C, laminar airflow 0.6 m/s, exposure time ≥ 5 minutes) → Filling (Servo-driven filling, ±0.5% accuracy, optional in-line check weighing) → Stoppering (Vacuum stoppering) → Capping (Capping acceptance rate ≥99.97%)

Core Modules

Control System & Data Integrity

All machines in the line are controlled by PLC systems with touch-screen HMI, supporting parameter setting, alarm management, and real-time status monitoring.
The filling machine is equipped with closed-loop control via in-line check weighing; the sterilization tunnel allows export of temperature profiles for validation purposes.
Selected modules are MES-ready and can be customized for system integration.

Washing & Sterilization Strategy

The vial washer adopts three-water / three-air spray combined with ultrasonic cleaning, ensuring full coverage without dead zones, and supports multi-stage rinsing with Purified Water and WFI.
The sterilization tunnel utilizes dry heat sterilization at 320 °C, with laminar airflow at 0.6 m/s and exposure time ≥ 5 minutes.
Three temperature zones are independently controlled, supporting thermal distribution validation, with endotoxin reduction ≥6 log.